Research

How do flexible circuits emerge in auditory cortical circuits?

In this project, we are interested in exploring the neural basis of flexible auditory behavior. By combining tractable rodent behavior, high-density silicon recording arrays, and novel analytical tools, we can explore when and where large ensemble activity is recruited for adaptive behavior. Using activity-dependent optogenetics we can establish causal relationships between ensemble activity patterns during different phases of learning. These experiments will yield a rich data set for exploring high-dimensional dynamics using computational models to determine whether ensembles in each learning phase evolve in their own subspace or interact in high-dimensional trajectories.

What are the network computations gating flexible auditory behavior?

Here, we are interested in exploring the network dynamics that gate flexible auditory behavior. We use simultaneous multi-region recordings to explore larger neural populations and how they interact during learning. To gain a more mechanistic understanding of how auditory learning is gated, we use spiking recurrent neural network models to examine the population-wide mechanisms which allow for behavioral flexibility and generate new hypotheses to test experimentally.

Hormonal regulation of auditory perception and learning

The lab also has an interest in understanding how sex hormones influence auditory perception, learning, and communication. These are exciting new avenues for the lab!